Selected work
Lin, J. Q.*, Khuperkar, D.*, Pavlou, S., Makarchuk, S., Patikas, N., Lee, F. C., Kang, J.N., ... & Mallucci, G. R. (2023). EMBO Journal.
Read the articleLin, J. Q.*, van Tartwijk, F. W.*, & Holt, C. E. (2020). Axonal mRNA translation in neurological disorders. RNA Biology.
Qamar, S.*, Wang, G.*, Randle, S. J.*, Ruggeri, F. S.*, Varela, J. A.*, Lin, J. Q.*, Phillips, E. C.*, Miyashita, A., Williams, D., Ströhl, F., … & St George-Hyslop, P. (2018). FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-pi Interactions. Cell.
Ströhl, F.*, Lin, J. Q.*, Laine, R. F., Wong, H. H., Urbančič, V., Cagnetta, R., Holt, C. E., & Kaminski, C. F. (2017). Single Molecule Translation Imaging Visualizes the Dynamics of Local β-Actin Synthesis in Retinal Axons. Scientific Reports.
Murakami, T.*, Qamar, S.*, Lin, J. Q.*, Schierle, G. S. K.*, Rees, E., Miyashita, A., ... Holt, C. E., Vendruscolo, M., Kaminski, C. F., & St George-Hyslop, P. (2015). ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function. Neuron.
From the archive
Cioni, J. M.*, Lin, J. Q.*, Holtermann, A. V., Koppers, M., Jakobs, M. A. H., Turner-Bridge, B., Azizi, A., Shigeoka, T., Franze, K., Harris, W. A., & Holt, C. E. (2019). Cell.
Read the article
Clifton N. E, Lin, J. Q.*, Holt C. E, O'Donovan M. C, & Mill J. (2023). Enrichment of the local synaptic translatome for genetic risk associated with schizophrenia and autism spectrum disorder. Biological Psychiatry.
van Tartwijk, F. W., Wunderlich, L. C., Mela, I., Makarchuk, S., Jakobs, M. A., Qamar, S., ... Lin, J. Q., Holt, C. E., & Kaminski, C. F. (2022). Mutation of the ALS/FTD-associated RNA-binding protein FUS alters axonal cytoskeletal organisation. bioRxiv.
Lin, J. Q., & Cioni, J. M. (2022). Live imaging of RNA transport and translation in Xenopus retinal axons. In Alessio Vagnoni (editor), Axonal Transport (pp. 49-69), Methods in molecular biology (Book Chapter).
Lu, M., van Tartwijk, F. W.*, Lin, J. Q.*, Nijenhuis, W., Parutto, P., Fantham, M., ... & Kaminski, C. F. (2020). The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes. Science Advances.
Ströhl, F.*, Lin, J. Q.*, van Tartwijk F. W., Wong, H. H., Holt, C. E., & Kaminski, C. F. (2020). A Protocol for Single-Molecule Translation Imaging in Xenopus Retinal Ganglion Cells. In Nobuhiko Yamamoto and Yasushi Okada (editors), Single Molecule Microscopy in Neurobiology, Neuromethods (Book Chapter).
Opstad, I. S., Ströhl, F., Fantham, M., Hockings, C., Vanderpoorten, O., van Tartwijk F. W., Lin, J. Q., … & Kaminski C. F. (2020). A waveguide imaging platform for live-cell TIRF imaging of neurons over large fields of view. J. Biophotonics.
Koppers, M., Cagnetta, R., Shigeoka, T., Wunderlich, L. C., Vallejo-Ramirez, P., Lin, J. Q., ... & Bellon, A. (2019). Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons. elife.
Shigeoka, T., Koppers, M., Wong, H. H. W.*, Lin, J. Q.*, Cagnetta, R.*, Dwivedy, A., ... & Schaeffer, J. (2019). On-site ribosome remodeling by locally synthesized ribosomal proteins in axons. Cell Reports.
St George-Hyslop, P., Lin, J. Q., Miyashita, A., Phillips, E. C., Qamar, S., Randle, S. J., & Wang, G. (2018). The Physiological and Pathological Biophysics of Phase Separation and Gelation of RNA Binding Proteins in Amyotrophic Lateral Sclerosis and Fronto-Temporal Lobar Degeneration. Brain Research.
Leung, K. M.*, Lu, B.*, Wong, H. H. W.*, Lin, J. Q., Turner-Bridger, B., & Holt, C. E. (2018). Cue-polarized transport of β-actin mRNA depends on 3′ UTR and microtubules in live growth cones. Frontiers in Cellular Neuroscience.
Shigeoka, T.*, Jung, H.*, Jung, J., Turner-Bridger, B., Ohk, J., Lin, J. Q., Amieux, P. S., & Holt, C. E. (2016). Dynamic axonal translation in developing and mature visual circuits. Cell.
Roque, C. G., Wong, H. H. W., Lin, J. Q., & Holt, C. E. (2016). Tumor protein Tctp regulates axon development in the embryonic visual system. Development.
*Equal Contributions