Neuronal RNA
Metabolism

From nucleus to synapse.

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Illustration of local translation in an axon
Axonal local translation illustration from the existing laboratory site.
Members of Lin Lab gathered for a meal

Lin Lab is a community of researchers across neuroscience, molecular biology, bioinformatics, and bioengineering.

Meet the people

Research

01

RNA Regulation

How editing, splicing, structure, and environmental conditions shape RNA fate.

Mechanism diagram for RBM3 regulation
02

Local Translation

How RNAs travel through neurons and are translated in the synaptic compartment.

Illustration of axonal local translation
03

Disease Mechanisms

How dysregulated RNA metabolism informs neurological disease mechanisms.

Microscopy image of a neuronal growth cone
Mechanism illustration from the RBM3 study

HNRNPH1 regulates the neuroprotective cold-shock protein RBM3 through poison exon exclusion.

EMBO Journal · 2023

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